Prevenar® 13 (Pneumococcal 13-valent Conjugate Vaccine, PCV)
Why to get 13-valent pneumococcal conjugate vaccine?
Pneumococcal infection represents a wide range of diseases caused by the bacterium Streptococcus pneumoniae (or more commonly referred as pneumococcus). While pneumococcus is a common cause of mild illnesses such as sinus or middle ear infections, it may also cause severe or even life-threatening invasive pneumococcal diseases (IPD) such as bacteremic pneumonia, sepsis, and meningitis.
Pneumococcal vaccination is one of the most effective means of preventing pneumococcal diseases. 13-Valent Pneumococcal Conjugate Vaccine (PCV13) is effective against both invasive pneumococcal disease and non-invasive pneumococcal pneumonia.
Who should get 13-valent pneumococcal conjugate vaccine?
The Scientific Committee on Vaccine Preventable Diseases (SCVPD) recommends
- children under 2 years of age to receive pneumococcal conjugate vaccines (PCV) under the Hong Kong Childhood Immunisation Programme (HKCIP). The standard regimen includes a primary series of 2 doses at 2 and 4 months and a booster dose at 12 months.
- high-risk individuals* aged 2 years or above to receive a single dose of 13-valent pneumococcal conjugate vaccine (PCV13), followed by a single dose of 23-valent pneumococcal polysaccharide vaccine (23vPPV) 1 year later. For those who have already received 23vPPV, a single dose of PCV13 should be administered 1 year after previous 23vPPV vaccination. For those who have already received PCV13, a single dose of 23vPPV should be administered 1 year after previous PCV13.
- for elderly 65 years of age and older without high-risk conditions*, either a single dose of PCV13 or a single dose of 23vPPV is recommended.
*High-risk conditions include:
- The elderly
- Newborn baby and children
- History of invasive pneumococcal disease;
- Immunocompromised states: Asplenia, HIV /AIDS , primary immunodeficiency; Immunodeficiencies related to malignancies and transplantation; Immunodeficiencies related to use of immunosuppressive drugs / systemic steroid
- Chronic disease: Chronic cardiac, pulmonary, liver or renal disease; Diabetes mellitus or Cerebrospinal fluid leakage
- With cochlear implants
(Essential hypertension per se is not considered as a high-risk condition)
Different factors such as age and clinical condition may affect the risk of pneumococcal disease. Patients with high-risk conditions should discuss with their attending doctors on the most appropriate vaccination regimen.
What are the side effects?
- Most people have no serious reactions after receiving PCV.
- Occasionally there may be mild fever (usually occur within 3 days after vaccination) or slight redness or swelling around the injection site, but these will gradually subside in a few days. If fever or discomforts persist, or abnormal breathing is observed, please consult a doctor immediately.
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