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1. Hospital Authority  (2021). Smart Patient-Stroke.  Retrieved 30 March 2021, from https:\/\/www21.ha.org.hk\/smartpatient\/SPW\/en-us\/Disease-Information\/Disease\/?guid=29ac1219-3d68-4378-a2bd-09e111da3650<\/p>\n\n\n\n

2. National Health Service. (3 August 2021). Stroke. Retrieved from<\/p>\n\n\n\n

https:\/\/www.nhs.uk\/conditions\/stroke\/<\/a><\/p>\n\n\n\n

3. Jeffrey L. Saver, M.D., John D. Carroll, M.D, et al Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke. N Engl J Med 2017; 377:1022-1032\/DOI: 10.1056\/NEJMoa1610057. <\/p>\n\n\n\n

4. Mohammad K Mojadidi, Muhammad O Zaman, Islam Y Elgendy et al Cryptogenic Stroke and Patent Foramen Ovale. J AM Coll Cardiol 2018 Mar 6;71(9):1035-1043.  doi: 10.1016\/j.jacc.2017.12.059.<\/p>\n\n\n\n

5. Mayo Clinic. (2 September 2021). Patent foramen ovale. Retrieved from<\/p>\n\n\n\n

https:\/\/www.mayoclinic.org\/zh-hans\/diseases-conditions\/patent-foramen-ovale\/symptoms-causes\/syc-20353487<\/a><\/p>\n\n\n\n

6. Cleveland Clinic. (15 July 2022). Patent Foramen Ovale (PFO). Retrieved from<\/p>\n\n\n\n

https:\/\/my.clevelandclinic.org\/health\/diseases\/17326-patent-foramen-ovale-pfo<\/a><\/p>\n\n\n\n

7. American Stroke Association. (18 September 2022). Cryptogenic Stroke or Stroke of Unknown Cause. Retrieved from<\/p>\n\n\n\n

https:\/\/www.stroke.org\/en\/about-stroke\/types-of-stroke\/cryptogenic-stroke<\/a><\/p>\n\n\n\n

8. Rothwell P. M. (2007). Making the most of secondary prevention. Stroke, 38(6), 1726. https:\/\/doi.org\/10.1161\/STROKEAHA.107.482265<\/p>\n\n\n\n

9. Walter N Kernan, Bruce Ovbiagele, Henry R Black et al Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack. 2014 Jul;45(7):2160-236.  doi: 10.1161\/STR.0000000000000024. <\/p>\n\n\n\n

10. Esther Boot, Merel Sanne Ekker, Junkanoo Putaala et al Ischaemic stroke in young adults: a global perspective. Journal of Neurology, Neurosurgery & Psychiatry 2020; 91: 411-417.<\/p>\n\n\n\n

11. Ebrahimi, H. A., Moghadam, A. H., & Aredestani, E. (2011). Evaluation of patent foramen ovale in young adults with cryptogenic stroke. ARYA atherosclerosis, 7(2), 74.<\/p>\n\n\n\n

12. Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke. Article in New England Journal of Medicine. September 2017, DOI: 10.1056\/NEJMoal1705915.<\/p>\n\n\n\n

13. Fleissner F, Frank P, Haverich A, Ismail I. Echocardiographic guided, transatrial closure of a patent foramen ovale. J Cardiothorac Surg. 2020;15(1):255. Published 2020 Sep 14. doi:10.1186\/s13019-020-01289-7.<\/p>\n\n\n\n

14. Cleveland Clinic. (2 May 2022). Thoracotomy. Retrieved from https:\/\/my.clevelandclinic.org\/health\/treatments\/22981-thoracotomy<\/a><\/p>\n\n\n\n

15. Brown KN, ElBebawy B, Shah AH, et al. Catheter Management Of Patent Foramen Ovale. [Updated 2022 May 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan.<\/p>\n\n\n\n

16. Steven R. Mess\u00e9, Gary S. Gronseth, David M. Kent et al Practice advisory update summary: Patent foramen ovale and secondary stroke prevention. 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